Peptide therapy Weight and metabolism

Retatrutide

What it is and what people take it for, in plain language.

Updated October 2026Further reading

What is Retatrutide?

A next-generation metabolic peptide that acts on three hormone receptors at once: GLP-1, GIP and glucagon. It is a different peptide from cagrilintide, which acts on the amylin receptor.

What do people take Retatrutide for?

Weight loss.

Should I talk to a physician about Retatrutide?

If you are considering it, or already using it, a physician can look at your history, your labs and your goals, and at what else might explain what you are hoping to change. At Aether Medicine in King of Prussia, near Philadelphia, or by video for patients in Pennsylvania.

Or call 484-806-1101

Further reading

  1. Jastreboff AM, et al. Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial. N Engl J Med. 2023. pubmed.ncbi.nlm.nih.gov/37366315/
  2. Jastreboff AM, et al. Retatrutide, a Triple Hormone Receptor Agonist, for Treatment of Obesity. N Engl J Med. 2026. pubmed.ncbi.nlm.nih.gov/42814954/

Educational information only, not medical advice. Reading this page does not create a physician-patient relationship.

Curious about Retatrutide?Talk to a physician about your goals. No payment online.